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These results, along with a earlier report showing that a small-molecule ACKR3 agonist CCX771 exhibits anxiolytic-like behavior in mice,2 assist the idea of targeting ACKR3 as a unique method to modulate the opioid technique, which could open new therapeutic avenues for opioid-related Issues.The complement is intended employing drug-free components
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These success, along with a former report showing that a small-molecule ACKR3 agonist CCX771 exhibits anxiolytic-like conduct in mice,two help the thought of concentrating on ACKR3 as a singular technique to modulate the opioid procedure, which could open new therapeutic avenues for opioid-similar Ailments.Importantly, these receptors have been obs